Endocrine Abstracts

Background: Patients with Cushing’s syndrome (CS) in remission often suffer from impaired quality of life and cognitive dysfunction. Mental fatigue is characterized by mental exhaustion which appears especially during sensory stimulation or following mentally strenuous tasks. Other typical features are long recovery time for restoration of mental energy, irritability, impaired memory and concentration and sensitivity to stress, light and noise. The primary aim of this stu...

Background: ACTH-independent Cushing syndrome (CS) accounts for 15–20% of endogenous CS. Approximately 10% of these patients have bilateral adrenal lesions where the differential diagnoses are primary bilateral adrenal macronodular hyperplasia (PBMAH), primary pigmented nodular adrenal disease (PPNAD), bilateral cortisol producing adenomas or a unilateral cortisol producing adenoma with a contralateral nonfunctioning adenoma. Also, the prevalence of subclinical CS is high...

Background: Patients with Cushing’s Syndrome (CS) suffer from a variety of neuropsychiatric and cognitive problems. Following remission, some, but not all of these symptoms resolve. Recent cross-sectional studies in patients with CS show persistent structural and functional brain abnormalities. However, longitudinal studies using magnetic resonance imaging, and a detailed neurocognitive assessment, performed before and after treatment, are not available.<p class="abs...

Background: It is still undetermined whether patients with Cushing’s disease (CD) in remission have an increased mortality. Most previous studies are limited by small numbers of patients and/or short follow-up time.Objective: To study mortality in a nation-wide cohort of patients with CD during long-term follow-up.Methods: Patients with ICD codes for Cushing’s syndrome and/or CD, between 1987 and 2013, were identified in ...